Common use Isotretinoin is a retinoid (derives from vitamin A, and is found in small quantities naturally in the body) used for the treatment of severe acne. It can be also used in other cases. Dosage and direction Take Accutane by mouth with a glass of water, with or without food. Avoid cutting, crushing or chewing this medicine. Do not take the medicine more often than it is prescribed. Do not give up taking it except on the advice of your doctor. It may need time for the medicine to help. Consult your doctor concerning proper dose for you. Precautions Inform your health care professional if you have any allergies or if you have diabetes, osteoporosis or other bone disorders, asthma, heart disease, kidney or liver problems. Avoid taking vitamin supplements that contain vitamin A. Avoid drinking alcohol and smoking while being treated with this medication. Aged people can be more sensitive to side effects of the medicine. Inform your doctor if you are pregnant or breast-feed. Contraindications Accutane should not be used by patients having demonstrated a reaction of hypersensitivity to it. Possible side effects The most common side effects are drowsiness, constipation, headache, dizziness, vomiting, diarrhea, skin rashes. A very serious allergic reaction rarely occurs. Many people using this medicine do not have serious side effects. Turn to your doctor or pharmacist for more details. In case you notice the effects not listed here, contact your doctor or pharmacist.